ICGEB annual course held in Trieste, Italy, covering topics including basic principles of mouse genetics, mutagenesis approaches, archiving, phenotyping, informatics and databases, quantitative traits, examples of disease model discovery and the use of mouse disease models as a therapeutic tool. (Artwork G. Bortolussi ICGEB Lab. Skeletal muscle fibers transduced with AAV vector expressing green fluorescent protein (eGFP). Nuclei are stained in blue (Hoechst).