Show notes
In this episode, drug discovery scientist Artem Evdokimov discusses the science of pharmaceutical development, from historical breakthroughs to the current landscape. He shares insights on antibiotics resistance, the obesity drug Ozempic, and technical details of drug screening methods like DNA-encoded libraries. The conversation covers the economics of drug development, the potential of AI, and broader philosophical questions about human health and medicine. Evdokimov emphasizes the importance of avoiding oversimplification in science while highlighting both the triumphs and ongoing challenges in pharmaceutical research.03:18 Historical Roots of Medicine05:33 Evolution of Drug Delivery Methods12:52 Modern Drug Discovery and Challenges45:39 Understanding the Drug Discovery Process47:30 Challenges in Gene Therapy49:26 Complexities of Human Physiology53:14 The Role of Receptors and Hormones01:28:12 The Selenium Shortage and Shampoo Dilemma01:28:54 Challenges in Drug Manufacturing and Distribution01:34:23 Antibiotic Resistance: A Growing Concern01:45:18 The Future of Drug Discovery and AI02:11:01 Exploring AI and Drug Discovery02:11:41 Outsourcing in Pharma: Pros and Cons02:13:56 High Throughput Screening and Machine Learning02:16:37 Challenges and Future of Drug DiscoveryFOLLOW US ON SOCIAL:Twitter @ https://x.com/632nmPodcastSubstack: https://632nmpodcast.substack.com/Michael Dubrovsky @ https://x.com/MikeDubrovskyMisha Shalaginov @ https://x.com/MYShalaginovXinghui Yin @ https://x.com/XinghuiYinSUBSCRIBE:Apple Podcasts: https://podcasts.apple.com/us/podcast/632nm/id1751170269Spotify: https://open.spotify.com/show/4aVH9vT5qp5UUUvQ6Uf6ORWEBSITE:https://www.632nm.com