Prayer should be ‘in the Spirit’“praying always with all prayer and supplication in the Spirit, being watchful to this end with all perseverance and supplication for all the saints—” (Ephesians Although the scriptures refer specifically to praying in tongues as praying ‘in the spirit’, more generally it refers to all prayer. God is a Spirit (John Mary Alice Isleib says: “Praying in the spirit doesn’t mean to pray just in tongues. What does is mean, then? It means to pray out of your spirit, aware of the presence of the Holy Spirit. It means to pray all prayer – all the different kinds of prayer – in the presence of the Holy Spirit, in the realm of the spirit, out of your inner man.”